Increasing Safe Outpatient Care for Emergency Department Patients With Acute Pulmonary Embolism: a Pragmatic Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1,703
- 试验地点
- 28
- 主要终点
- Rate of home discharge from the emergency department following treatment for pulmonary embolism
研究概览
简要总结
To evaluate the impact of an integrated electronic clinical decision support system to facilitate risk stratification and site-of-care decision-making for patients with acute pulmonary embolism.
详细描述
Many low-risk emergency department patients with acute pulmonary embolism are routinely hospitalized despite being eligible for outpatient care. One impediment to home discharge is the difficulty of identifying which patients can safely forego hospitalization. This pragmatic clinical trial intends to evaluate the effect on emergency department disposition of a multicomponent intervention, including electronic clinical decision support system access, physician education, and physician-specific audit and feedback. The hypothesis for this study is that intervention sites, when compared with concurrent control sites, will see an increase in home discharges without an increase in 5-day pulmonary embolism-related return visits or 30-day all-cause mortality.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Acute objectively-confirmed pulmonary embolism, diagnosed in the emergency department
排除标准
- •Comfort-care only
- •Left the ED against medical advice
- •Current PE radiologically diagnosed >12 hrs prior to arrival
- •Recent DVT or PE diagnosed within 30 days
研究组 & 干预措施
Intervention
干预措施: Integration of electronic clinical decision support (Other)
Control
结局指标
主要结局
Rate of home discharge from the emergency department following treatment for pulmonary embolism
时间窗: 8 months post-implementation compared to 8 months pre-implementation
次要结局
- Number of participants with major hemorrhage, recurrent venous thromboembolism, and all-cause mortality(30 days)
- Number of participants with return visits for pulmonary embolism-related signs, symptoms, or interventions(5 days)
