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Suture Fixation System Versus Tendonous Reconstruction in Carpometacarpal (CMC) Arthroplasty

Not Applicable
Completed
Conditions
Thumb Carpometacarpal Arthritis
Interventions
Procedure: Ligament reconstruction with suture fixation system
Procedure: Ligament Reconstruction with Tendon Interposition (LRTI)
Registration Number
NCT01121874
Lead Sponsor
J&M Shuler
Brief Summary

Thumb carpometacarpal (CMC) arthritis affect 1 in 4 females and 1 in 12 males. Patients who fail to respond to conservative treatment may benefit from surgery; however, controversy exists over the most effective surgical technique. A popular technique, ligament reconstruction with tendon interposition (LRTI) involves a trapeziectomy, followed by reconstruction of the palmar oblique ligament using a harvested flexor tendon from the wrist.

We believe that use of a suture fixation system to reconstruct the palmar oblique ligament, instead of harvesting a wrist tendon, may provide a superior repair. The objective of this study is to compare functional outcome measurements among patients who receive CMC arthroplasty using a suture fixation system (investigational group) to those who receive LRTI surgery (control group). We hypothesize that patients in the investigational group will demonstrate superior functionality, compared to patients in the control group.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
53
Inclusion Criteria
  • Male or female patients aged >18.
  • Eaton Stage III or IV CMC arthritis
  • Failure to respond to conservative treatment
Exclusion Criteria
  • Previous surgical interventions on that thumb
  • Upper extremity neurological dysfunction
  • Inability to effectively communicate with the research staff, due to hearing impairment, cognitive impairment, or a language barrier
  • Unwilling or unable to provide written informed consent

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Suture fixation systemLigament reconstruction with suture fixation systemCMC arthroplasty which reconstructs palmar oblique ligament using a suture fixation system.
Suture fixation system + 2 week immobilizationLigament reconstruction with suture fixation systemCMC arthroplasty which reconstructs palmar oblique ligament using a suture fixation system, and with a decreased immobilization time from 6 to 2 weeks post-surgery.
LRTILigament Reconstruction with Tendon Interposition (LRTI)These patients will undergo ligament reconstruction with tendon interposition (LRTI) surgery. They will serve as a control group, against which to compare the investigational surgical technique.
Primary Outcome Measures
NameTimeMethod
Overall functionalityBaseline

Functionality will be assessed using the Disabilities of the Arm, Shoulder, and Hand (DASH) questionnaire, which assesses functionality of the upper extremity, and Short Form 36 (SF-36) health outcomes assessment, which quantifies global functionality (not specific to the upper extremity).

Overall Functionality24 months
Secondary Outcome Measures
NameTimeMethod
Analog pain scaleBaseline, 2 wks, 6 wks, 3 mos, 6 mos, 12 mos, 24 mos

Pain will be assessed using the visual analog pain scale, which asks the patient to rate their pain on a scale from 1 to 10.

Strength measuresBaseline, 6 wks, 3 mos, 6 mos, 12 mos, 24 mos

Strength will be assessed via key and tip pinch strength and grip strength, using a dynamometer

Range of motionBaseline, 6 wks, 3 mos, 6 mos, 12 mos, 24 mos

Range of motion (ROM) will be assessed via radial and palmar abduction (degrees) and opposition (cm).

Scaphometacarpal distanceBaseline, 6 wks, 3 mos, 6 mos, 12 mos, 24 mos

Distance between the distal pole of the scaphoid and the proximal aticular surface of the metacarpal. Taken in stressed and relaxed views

Operative timeBaseline, 6 wks, 3 mos, 6 mos, 12 mos, 24 mos

Operative time in minutes

Trial Locations

Locations (1)

Athens Orthopedic Clinic

🇺🇸

Athens, Georgia, United States

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