Clinical Applications of Domperidone in Patients With Delayed Gastric Emptying
Not Applicable
Completed
- Conditions
- Digestive System Disease
- Interventions
- Other: Domperidone
- Registration Number
- NCT01844622
- Lead Sponsor
- Mt. Sinai Medical Center, Miami
- Brief Summary
The purpose of the study is to treat patients with on-going slow stomach emptying(gastroesophageal reflux disease), who have failed to respond to standard therapy
- Detailed Description
This is a study on the effectiveness of domperidone, which increases movement through the digestive system for relief of symptoms, in patients who have delayed gastric solid-phase emptying
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 37
Inclusion Criteria
- Persistent esophagitis
- Heartburn
- Nausea
- Vomiting
- Severe dyspepsia
- Severe chronic constipation
Exclusion Criteria
- History of, or current arrhythmias including ventricular tachycardia, - Ventricular fibrillation and Torsade des Pointes.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Domperidone Domperidone Domperidone will be given at 10 mg before each meal and at bedtime. At completion of the study, patients will receive standard medical therapy
- Primary Outcome Measures
Name Time Method Clinical Applications of Domperidone in Patients with Refractory Gastroesophageal Reflux Disease (GERD)or Delayed Gastric Solid-Phase Emptying 5 years GERD or Delayed Gastric Emptying
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (2)
Mt. Sinai Medical Center, Division of Gastroenterology
🇺🇸Miami Beach, Florida, United States
Division of Gastroenterology, Mt. Sinai Medical Center
🇺🇸Miami Beach, Florida, United States