Clinical Applications of Domperidone in Patients With Delayed Gastric Emptying

Not Applicable

Completed

• Conditions: Digestive System Disease

• Registration Number: NCT01844622
• Lead Sponsor: Mt. Sinai Medical Center, Miami

Brief Summary

The purpose of the study is to treat patients with on-going slow stomach emptying(gastroesophageal reflux disease), who have failed to respond to standard therapy

Detailed Description

This is a study on the effectiveness of domperidone, which increases movement through the digestive system for relief of symptoms, in patients who have delayed gastric solid-phase emptying

Study Timeline

• Study Start: 2007-12
• Study First Submitted: 2013-04-29
• Study First Submitted QC: 2013-04-30
• Study First Posted: 2013-05-01
• Primary Completion: 2015-02-19
• Study Completion: 2015-02-19
• Status Verified: 2017-05
• Last Update Submitted: 2017-05-15
• Last Update Posted: 2017-05-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 37

Inclusion Criteria

• Persistent esophagitis
• Heartburn
• Nausea
• Vomiting
• Severe dyspepsia
• Severe chronic constipation

Exclusion Criteria

• History of, or current arrhythmias including ventricular tachycardia, - Ventricular fibrillation and Torsade des Pointes.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Clinical Applications of Domperidone in Patients with Refractory Gastroesophageal Reflux Disease (GERD)or Delayed Gastric Solid-Phase Emptying	5 years	GERD or Delayed Gastric Emptying

Trial Locations

Locations (2)

Division of Gastroenterology, Mt. Sinai Medical Center; 🇺🇸 Miami Beach, Florida, United States

Mt. Sinai Medical Center, Division of Gastroenterology; 🇺🇸 Miami Beach, Florida, United States