Evaluation of the efficacy and safety of inhaled magnesium sulfate in combination with standard treatment in Covid-19 patients
Phase 3
Recruiting
- Conditions
- Covid-19.COVID-19, virus identifiedU07.1
- Registration Number
- IRCT20191211045691N1
- Lead Sponsor
- ational Research Institute of Tuberculosis and Lung Diseases(NRITLD), Masih Daneshvari Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
Minimum age 18 and maximum age 80 years
Candidate for hospitalization ( o2sat<93% ?? RR>24 ?? Pao2/Fio2<300)
The first 24 hours or 48 hours of hospitalization
Signing up the informed consent form
Exclusion Criteria
Patients with heart block
Patients with myocardial injury
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Improve respiratory symptoms including shortness of breath and cough. Timepoint: Days 1 to 5 and at the end of the first week. Method of measurement: Questionnaire.;Blood o2 saturation. Timepoint: Just before and 1 hour after prescribe medication. Method of measurement: Pulse oximetry device.
- Secondary Outcome Measures
Name Time Method C-reactive protein. Timepoint: C-reactive protein is measured daily for days 1 to 5. Method of measurement: Measurement of C-reactive protein is performed by a laboratory sample of blood taken from the patient.;Total number of lymphocytes. Timepoint: The total number of lymphocytes is measured daily for days 1 to 5. Method of measurement: Measurement of The total number of lymphocytes is performed by a laboratory sample of blood taken from the patient.;D-dimer test. Timepoint: The D-dimer test is measured daily for days one to five. Method of measurement: The D-dimer test is performed with a blood sample taken from the patient by a laboratory.;Ferritin. Timepoint: Ferritin is measured daily for days 1 to 5. Method of measurement: Measurement of ferritin is performed by a laboratory sample of blood taken from the patient.