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Does magnesium sulphate reduce length of stay and improve spirometry in acute moderate to severe asthma when initial treatment fails?

Not Applicable
Completed
Conditions
asthma
Respiratory - Asthma
Registration Number
ACTRN12612000838819
Lead Sponsor
maureen busuttil
Brief Summary

insufficient numbers for meaningful statistical analysis of the effects of magnesium in the study cohort.

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
42
Inclusion Criteria

Acute asthma exacerbation requiring attendance to an emergency department

Exclusion Criteria

life threatening asthma
pregnancy
other respiratory diseases eg pulmonary embolis,pneumonia

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
discharge from hospital[4 hours post intervention ( treatment with magnesium)];total duration of stay in hospital in hours[from time of enrollment to discharge from hospital]
Secondary Outcome Measures
NameTimeMethod
Improvement in lung function as measured by spirometry[4 hours post intervention and at followup 72 hours post intervention];withdrawl from trial[at any time from enrolment to 4 hours post intervention];need for admission to intensive care[from time of enrollment to discharge from hospital];need for invasive or non invasive ventilation[from time of enrollment to discharge from hospital]
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