Atlas Predicted DBS Settings in Essential Tremor

Not Applicable

Terminated

• Conditions: Essential Tremor
• Interventions: Device: Change DBS programming

• Registration Number: NCT02678429
• Lead Sponsor: Vanderbilt University

Brief Summary

Programming Deep Brain Stimulation for the treatment of Essential Tremor can be a time intensive process. Using an atlas created using functional tremor responses in the operating room to determine the optimal settings would lead to a faster response for the patient and improved quality of life.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2016-02-05
• Study First Submitted QC: 2016-02-08
• Study First Posted: 2016-02-09
• Study Start: 2016-09
• Primary Completion: 2021-11-19
• Study Completion: 2021-11-19
• Results First Submitted: 2022-11-30
• Status Verified: 2023-03
• Results First Submitted QC: 2023-03-24
• Last Update Submitted: 2023-03-24
• Results First Posted: 2023-03-27
• Last Update Posted: 2023-03-27

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 4

Inclusion Criteria

Seleced for DBS of the VIM nucleus at Vanderbilt Medical center Diagnosis of essential tremor

Exclusion Criteria

Unable to use the patient handheld programmer

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
DBS programming, standard of care	Change DBS programming	DBS settings determined from the standard Neurologist symptomatic response first then change to settings from Atlas
DBS progamming from Atlas	Change DBS programming	DBS settings determined from the a functional atlas first then change to settings determined by standard of care

Primary Outcome Measures

Name	Time	Method
Fahn-Tolusa-Marsden Tremor Rating Scale	1 month	Tremor quantification

Trial Locations

Locations (1)

Vanderbilt University; 🇺🇸 Nashville, Tennessee, United States