comparative evaluation of antimicrobial efficacy and periapical healing with conventional irrigation versus adjunctive laser disinfection during endodontic treatment of anterior teeth :A Randomized clinical trial
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- 1. antimicrobial efficacy
研究概览
简要总结
comparative evaluation of antimicrobial efficacy and periapical healing with conventional irrigation versus adjunctive laser disinfection during endodontic treatment of anterior teeth :A Randomized clinical trial
This study evaluates the antimicrobial efficacy and periapical healing with conventional irrigation versus adjunctive laser disinfection during endodontic treatment of anterior teeth .The total sample size of the study is 40and the study period is 18 months.
Null hypothesis states that There is no significant difference in the CFU reduction and periapical healing between conventional irrigation and adjunctive laser disinfection.
Outcome are assessed as follows, 1)antimicrobial efficacy determined by colony forming unit count in root canal using microbiological analysis. 2)periapical healing evaluated by radiographic assessment at 3,6 and 12 months.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 55.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Patient requiring root canal treatment of anterior teeth having chronic apical periodontitis with score 4 periapical index ( PAI)
- •Healthy male and female patients, aged between 18 to 55 years
- •Teeth with a single root canal and no history of prior endodontic treatment.
排除标准
- •1.Systemic disorders that could weaken the immune system.
- •The use of anti-inflammatory drugs or antibiotics within the past 3 months.
- •The requirement for antibiotic prophylaxis prior to dental treatment.
- •Calcified canals.
- •Developmental anomalies.
结局指标
主要结局
1. antimicrobial efficacy
时间窗: 1. antimicrobial efficacy evaluated immediately after treatment | 2. Periapical healing evaluated by radiographic assessment at 3,6and 12 months
2. Periapical healing
时间窗: 1. antimicrobial efficacy evaluated immediately after treatment | 2. Periapical healing evaluated by radiographic assessment at 3,6and 12 months
次要结局
未报告次要终点
研究者
Dr Saranya k
Dr.Jayasree S, Govt dental college ,Kozhikode