Clinical study to validate the safety and efficacy of joshanda ( Darchini, Saleekha, Saad, Bisbasa and Qaranfal) in the management of Warm-e-Ghudda-e-Mazi (Benign Prostatic Hyperplasia): An open label, randomized, standard control study .

Benign prostate hyperplasia (BPH) is the expansion of prostate gland in elderly men, which can cause partial or complete bladder outlet obstruction producing them to have lower urinary tract symptoms. It is a common urological disease among older men. The age specific prevalence of BPH has been estimated to be 8% in the fourth decade of life, 50% in the sixth decade of life and 80% in the ninth decade of life . Since BPH itself is not lethal, urine flow obstruction is its most significant outcome that has a negative impact on person’s ability to engage in physical activity and their mental health. Dribbling of urine, frequent micturation especially at night, a hesitant, interrupted or weak stream of urine, sense of incomplete bladder emptying are some symptoms of BPH. BPH has been described under the headings of Warm-e- Ghudda-e-Mazi,Salaa-e--Ghudda-e-Mazi ,and Warm-e- Unaq-e- Masaana in Unani system of medicine. However, symptomatic BPH treatment is typically found in our classical writings under several categories such as Ehtabas-e-baul , Taqteer-ul -baul and Usr-e-baul . The symptoms and the size of the prostate can be reduced with medical therapy, however allopathic medicine does have number of negative effects. Since ancient times, Unani physicians have used secure herbal treatments to treat the BPH symptoms. However, there are not enough credible scientific studies to backup this practice. Scientific confirmation of these safe medications is urgently required. The purpose of the current study is to find a safe and effective treatment for BPH by examining how polyherbal Unani formulation affects BPH  patients.