A randomized, double-blind controlled trial on the effects of the mouthrinse containing edible mushroom (shiitake) extract on dental plaque acidogenicity and microbial compositio
Completed
- Conditions
- caries preventiecariesdental decay
- Registration Number
- NL-OMON33940
- Lead Sponsor
- Vrije Universiteit
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
Healthy males and females that would:
* Be 18 years of age or older
* Be in good general health as determined by the investigator based on a review of the medical history/update
* Possess at least three posterior teeth (premolars/molars) in each quadrant (with no partial dentures, orthodontic banding or wires)
Exclusion Criteria
* Have not passed all inclusion criteria
* Have used antibiotics less than three months prior the start of the study
* Have untreated caries or periodontal disease
* Have reduced stimulated salivary flow (< 0.7 ml/min)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Amount of organic acids in plaque and microbial composition of plaque before<br /><br>and after each test period</p><br>
- Secondary Outcome Measures
Name Time Method <p>Amount of dental plaque before and after each test period</p><br>