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临床试验/NCT01059032
NCT01059032已完成1 期

Enhancement and Restoring of Low Dose Abdominal CT Images by a Novel Adaptive Nonlinear 3D Post Processing Filter - a Prospective Blinded Interventional Study

Lars Borgen2 个研究点 分布在 1 个国家目标入组 12 人开始时间: 2009年12月最近更新:
适应症

试验速览

阶段
1 期
状态
已完成
发起方
入组人数
12
试验地点
2
主要终点
Rating of image quality

研究概览

简要总结

Through the rapid growth of multislice Computer Tomography (CT) imaging, radiation protection has become a major issue in the radiological community. Optimizing CT scanning is a key task when keeping the radiation doses as low as reasonable achievable (the ALARA principle). Post processing filters can improve and restore grainy and noisy low dose CT images by enhancing structure and reducing image noise. In our study of 10 patients, the investigators perform a preliminary evaluation of a novel post processing filter, which does picture element correlations in all three spatial dimensions. By comparing normal dose pictures with unprocessed low-dose pictures and pictures processed with two dimentional (2D) and three dimentional (3D) filters,the investigators will be able to assess the possible clinical value of the 3D filter. This project is collaboration between Buskerud Hospital (BU), Buskerud University College, Norwegian Radiation Protection Authority (NRPA) and Center for Medical Image Science and Visualization (CMIV). The project is part of the PhD of Lars Borgen.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Diagnostic
盲法
Double (Participant, Investigator)

入排标准

年龄范围
60 Years 至 90 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Outpatients, Male or female,Age above 60 years, Referred to our department for an abdominal CT with intravenous contrast.

排除标准

  • Abdominal diameter less than 80cm or larger than 100cm, Gross pancreatic pathology, Gross anatomic anomalies in the investigated region, Intolerance of intravenous contrast

结局指标

主要结局

Rating of image quality

时间窗: 3-6 months

次要结局

未报告次要终点

研究者

发起方
Lars Borgen
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Lars Borgen

MD

University of Oslo

研究点 (2)

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