Treatment of gum disease to reduce cardiovascular risk

Phase 1

Recruiting

• Conditions: Coronary artery disease; Periodontitis; Cardiovascular - Coronary heart disease; Oral and Gastrointestinal - Other diseases of the mouth, teeth, oesophagus, digestive system including liver and colon

• Registration Number: ACTRN12619001573145
• Lead Sponsor: Western Sydney Local Health District

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-11-14
• Last Update Posted: 16 October 2022

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

have coronary artery disease
- hsCRP >2mg/L
- have moderate-severe periodontitis
- are currently on statin therapy

Exclusion Criteria

Have received subgingival scaling and root planning in the last 6 months
• Are currently taking or have had antibiotic therapy in the last 3 months
• Are currently pregnant or planning pregnancy
• Are currently lactating/breastfeeding
• Have renal impairment
• Have hepatic impairment
• Have blood dyscrasias
• Are taking medications which interact with colchicine
• Have Type 1 Diabetes Mellitus
• Have moderate or severe periodontitis
• Have urgent and/or extensive dental therapy needs that will hinder periodontal treatment

Study & Design

• Study Type: Interventional
• Study Design: Not specified