Effects of Physical-Cognitive Training With Different Task Models on Dual-Task Walking in Parkinson's Disease With Mild Cognitive Impairment
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 27
- 试验地点
- 1
- 主要终点
- Change from baseline dual-task walking performance at 8 weeks
研究概览
简要总结
The present study will characterize exercise model effects (integrated model vs. consecutive model) of physical-cognitive exercise on dual-task walking control in Parkinson's disease with mild cognitive impairment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 40 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •a diagnosis of idiopathic Parkinson's disease
- •have decreased cognitive functions but do not interfere with functional independence
- •Montreal Cognitive Assessment (MoCA): 21-25
- •able to walk independently without walking devices for at least 10 meters and with the ability to turn 180°
排除标准
- •a diagnosis of dementia
- •other diseases that may influence cognitive functions or walking performance
- •a history of brain surgery
- •modification of the medication during the exercise intervention
研究组 & 干预措施
Consecutive training model
Participants in this group will accept postural and cognitive training separately and for identical durations (both 30 minutes).
Each training session will last for 70 minutes, twice a week, and 12 sessions in total.
干预措施: Consecutive physical-cognitive training (Behavioral)
Integrated training model
Participants in this group will accept postural and cognitive training at the same time, e.g. naming animals while standing on the foam.
Each training session will last for 70 minutes, twice a week, and 12 sessions in total.
干预措施: Integrated physical-cognitive training (Behavioral)
结局指标
主要结局
Change from baseline dual-task walking performance at 8 weeks
时间窗: 8 weeks
Change from baseline Montreal Cognitive Assessment (MoCA) score at 8 weeks
时间窗: 8 weeks
MoCA: 0-30 points, higher scores mean a better outcome
Fall frequency
时间窗: 20 weeks
次要结局
未报告次要终点