A pragmatic randomised controlled trial evaluating acupuncture as an antenatal intervention for the treatment of antenatal depression.

Antenatal depression is common, with wide-ranging detrimental consequences. Despite this, symptomologies are frequently inadequately managed. Consequently, women seek out alternatives. Preliminary evidence suggests acupuncture may provide a safe and potentially effective adjunct treatment. This study further examined this possibility. In this RCT, fifty-seven women meeting Edinburgh Postnatal Depression Scale (EPDS) scores greater than or equal to 13 were randomised to either individually tailored, depression specific acupuncture, progressive muscle relaxation (PMR) comparator, or treatment as usual. Women were also interviewed regarding their experiences of receiving acupuncture. Focus groups were in addition conducted with midwives to ascertain their views of the study. Findings demonstrated significantly reduced end of the intervention EPDS, stress component of the Depression, Stress and Anxiety scale, and Kessler 6 scores in the acupuncture group, when compared to the PMR and treatment as usual control groups. Mean cortisol: DHEA ratios were in addition significantly increased in the acupuncture group when compared to treatment as usual. Interviews confirmed acupuncture recipients perceived benefits. Midwives also reported receiving positive feedback from participants regarding benefits, as well as observing the improved disposition of recipients. Findings suggest acupuncture reduced or buffered stress, increased coping, and improved psychological well-being.