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Effects of folic acid on the human microcirculation: a randomized, doubleblind, placebo-controlled study.

Completed
Registration Number
NL-OMON23261
Brief Summary

/A

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
58
Inclusion Criteria

1. Age: 25-55;

2. BMI > 25 and BMI < 30;

Exclusion Criteria

1. Medication affecting cardiovascular function;

2. systolic bloodpressure > 160;

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
1. Endothelium-dependent and endothelium-independent skin blood flow using laser-doppler fluxmetry combined with iontophoresis;<br /><br>2. nailfold video capillaroscopy.
Secondary Outcome Measures
NameTimeMethod
1. (Ambulatory) blood pressure;<br /><br>2. vascular resistance;<br /><br>3. cardiac output.
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