Effects of folic acid on the human microcirculation: a randomized, doubleblind, placebo-controlled study.
Completed
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 58
Inclusion Criteria
1. Age: 25-55;
2. BMI > 25 and BMI < 30;
Exclusion Criteria
1. Medication affecting cardiovascular function;
2. systolic bloodpressure > 160;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Endothelium-dependent and endothelium-independent skin blood flow using laser-doppler fluxmetry combined with iontophoresis;<br /><br>2. nailfold video capillaroscopy.
- Secondary Outcome Measures
Name Time Method 1. (Ambulatory) blood pressure;<br /><br>2. vascular resistance;<br /><br>3. cardiac output.