Linking High-Risk Jail Detainees to HIV Pre-Exposure Prophylaxis: PrEP-LINK
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 100
- 试验地点
- 14
- 主要终点
- Satisfaction of the Utilization of the CHW to Aid in Accessing PrEP Assessed by the Client Satisfaction Questionnaire-Revised
研究概览
简要总结
Our proposed study will: provide a novel exploration of facilitators and barriers to PrEP; allow us to target hard to reach populations, including men who have sex with men (MSM) and substance users (both of which are top funding priority groups for the National Institutes of Health) who experience intersecting markers of HIV risk; and inform regional, and possibly national, intervention approaches to combat the overlapping epidemic of HIV and incarceration.
详细描述
Specific Aims
The specific aims of the project associated with this protocol are:
Aim 1: Perform a qualitative assessment of facilitators and barriers to PrEP uptake among high-risk jail detainees, systems and interactor levels. To achieve this aim we will conduct qualitative interviews with three distinct groups of stakeholders:
- Systems interviews (n=6);
- Interactor interviews (n=8); and
- Individual Key Informant interviews (n=20).
Within each of these strata, we aim to collect data representing diverse perspectives with respect to interest, knowledge, attitudes, and barriers (including substance use) to PrEP uptake. We will also explore acceptability and feasibility of an intervention to link individuals being released from the Pulaski County jail to PrEP services.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age greater than or equal to 18 at study enrollment
- •Able to understand and speak English and to provide written and verbal informed consent.
- •Able to provide reliable pieces of locator information (e.g. mailing address, phone number, email address, places frequently visited, etc.)
- •HIV negative confirmed through an on-site rapid HIV test;
- •Recently released from the Pulaski County Regional Detention Facility into the community and not into another detention facility or recently released (within 30 days) from a correctional facility and residing in Central Arkansas.
- •At substantial risk for HIV as determined by CDC/WHO PrEP guidelines, which includes engaging in any of the following behaviors in the last six months:
- •Having condomless vaginal or anal sex with more than one partner,
- •Having a sex partner with one or more HIV risk (e.g. PWID, a sex worker),
- •Being diagnosed with a STI,
- •Reporting history of sharing injection material/equipment, or
- •Having a sexual partner who is HIV positive.
排除标准
- •Potential participants unable to provide informed consent, including people with severe mental illness requiring immediate treatment or with mental illness limiting their ability to participate (e.g., dementia), will be excluded.
结局指标
主要结局
Satisfaction of the Utilization of the CHW to Aid in Accessing PrEP Assessed by the Client Satisfaction Questionnaire-Revised
时间窗: 12 months
The acceptability of the intervention will be determined with descriptive statistics of the participants' acceptability ratings, including whether they think the intervention is acceptable. Acceptability is defined as \> 80% of participants expressing high satisfaction with the intervention based on the Client Satisfaction Questionnaire - Revised (CSQ-8). The CSQ-8 is scored using a scale which ranges from 8-32, with a higher number indicating greater satisfaction.
Rate of PrEP Uptake Among Participants Based on Medical Chart Review
时间窗: 12 months
The preliminary efficacy of the intervention will be determined by assessing the primary outcome of PrEP uptake by looking at the medical charts of the participants. A secondary outcome will be PrEP adherence defined by participants who were adherent to the medication determined by self-report at 6, and 12 months.
次要结局
- Rate of PrEP Adherence and Retention Based on Self-reported Surveys (PrEP-Use, PrEP-Attitude, PrEP-Adherence)(6 months)