Cool water foot immersion, skin wetting and fan use as low-cost, at home cooling strategies for older adults during heat waves

Not Applicable

Recruiting

• Conditions: Heat related cardiovascular strain; Heat related thermal strain; Heat related changes in thermal perceptions (i.e., comfort and sensation); Injuries and Accidents - Other injuries and accidents; Cardiovascular - Normal development and function of the cardiovascular system; Public Health - Other public health

• Registration Number: ACTRN12622000367741
• Lead Sponsor: The University of Sydney

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-03-02
• Last Update Posted: 3 June 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 41

Inclusion Criteria

Healthy Cohort (The University of Sydney, Sydney AU):
- 60+ years
- Non-smoker or ex-smoker (quit greater than 2 y prior)
- Otherwise healthy
- No difficult understanding or speaking English

CAD Cohort (Montreal Heart Institute, Montreal CA):
-Age between 50 and 80 years.
-History of angiographic coronary artery disease (greater than or equal to 70% arterial diameter narrowing of at least one major epicardial coronary artery) and/or prior coronary revascularization and/or documented prior acute coronary syndrome and/or stable angina and/or perfusion defect during exercise or pharmacological stress testing.

Exclusion Criteria

Healthy Cohort (The University of Sydney, Sydney AU):
-Body mass index greater than or equal to 40 kg/m2.
-Hormonal replacement therapy.
-Uncontrolled hypertension (greater than 180/110 mmHg).
-Uncontrolled diabetes or severe complications of diabetes.
-Evidence of severe renal disease, liver disease, cerebrovascular disease, pulmonary disease, endocrine abnormalities, cognitive impairment, psychiatric disorder, substance abuse, degenerative neurological condition or any other medical condition deemed to pose risk during the study visits.
-Medication known to cause hyper- or hypo-hidrosis (except those taken for hypertension).
-Currently taking a beta-blocker.
-Evidence of current fluid and electrolyte disorders
-Current diagnosis of anemia
-Abnormal thyroid function
-Arrhythmias at rest or during cardiac stress test
-Significant cognitive impairment, psychiatric disorder, substance abuse, degenerative neurological condition
-Any other medical condition deemed to pose risk during the proposed testing or experiments, or preclude them from completing the screening stress test.

CAD Cohort (Montreal Heart Institute, Montreal, CA):
-CAD-related hospitalisation or changes in cardiac medications or change in pattern of angina less than 3 months prior to enrolment.
-Body mass index greater than or equal to 40 kg/m2.
-Hormonal replacement therapy (less than 1 year) for female participants.
-Uncontrolled hypertension (greater than 180/110 mmHg).
-Uncontrolled diabetes or severe complications of diabetes.
-Recent (less than 3 months) coronary bypass surgery.
-Ejection fraction less than 40% and/or clinical evidence/history of heart failure.
-Significant valve heart disease.
-Resting ECG abnormalities interfering with observation of ST segment changes during testing.
-Evidence of severe renal disease, liver disease, cerebrovascular disease, pulmonary disease, endocrine abnormalities, cognitive impairment, psychiatric disorder, substance abuse, degenerative neurological condition or any other medical condition deemed to pose risk during the study visits.

Study & Design

• Study Type: Interventional
• Study Design: Not specified