Investigation of Calendula officinalis extract on radiotherapy-induced oral mucositis

Phase 2

• Conditions: Oral Mucositis.; Other and unspecified lesions of oral mucosa

• Registration Number: IRCT201106076734N1
• Lead Sponsor: Vice chancellor for research, Babol University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

1) Minimum accumulative dose of 40 Gy according to treatment protocol; 2) Complete exposure of oral field to x ray; 3) Minimum age of 45;
Exclusion criteria were: 1) Pregnancy; 2) Allergy to the mouthwash; 3) Preexisting oral conditions; 4) Use of other medications related to oral mucositis during study period; 5) Any systemic diseases interfering with healing

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Intensity of oral mucositis. Timepoint: at the end of each week for total of 6 weeks for each patient. Method of measurement: Oral Mucositis Assessment Scale (OMAS).