The influence of Maternal Antibiotic use on Microbial colonisation in Infants
Recruiting
- Conditions
- Cesarean section, keizersnedeVaginal delivery, vaginale partusIntestinal colonization, intestinal kolonisatieMicrobiota, microbioomAntibiotics, antibiotica
- Registration Number
- NL-OMON26831
- Lead Sponsor
- VU medical center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
Mother:
- Delivery at a gestational age > 36+6 weeks
Exclusion Criteria
Mother:
- Age < 18 years
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ƒ{1. To describe and compare intestinal microbiome colonisation (by means of IS-pro) of neonates born by cesarean section, in terms of timimng of antibiotics treatment: prior to caesarean section (NVOG protocol) or after clamping of the umbilical cord (currently used protocol).
- Secondary Outcome Measures
Name Time Method ƒ{-To describe and compare intestinal microbiome colonisation of vaginally delivered neonates with those born by caesarean section by means of IS-pro analysis. <br /><br>- To evaluate effects of maternal vaginal and rectal microbiota composition on neonatal gut microbiota colonisation.<br>