Effects of Snuff and/or Red Wine om Metabolic Rate
- Conditions
- Metabolic RateHungerInsulin Sensitivity
- Registration Number
- NCT04547426
- Lead Sponsor
- University Hospital, Linkoeping
- Brief Summary
About 14 healthy participants, consume a standardized breakfast combined with either using regular or nicotine-free moist snuff. The metabolic rate is measured every hour for four hours on each occasion starting in the morning. Participants are also randomized to get red wine or non-alcoholic red wine to the meal.
- Detailed Description
About 14 healthy participants, consume a standardized breakfast combined with either using regular or nicotine-free moist snuff. The metabolic rate is measured measured before the meal and then every hour for a total of four hours on each occasion that starts in the morning. Participants are also randomized to get red wine or non-alcoholic red wine to the meal. Since there are four possible combinations of the wine and the snuff, all participants do the test on four occasions. Except for metabolic rate we will also analyze hormone responses regarding appetite or hunger.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 14
No significant disease -
known illnesses, thyroid disease, need to take prednisolone, psychiatric disease,inability to understand Swedish
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Primary Outcome Measures
Name Time Method level of metabolic rate 4 hours Measurement of metabolic rate by registration of CO2 in breath and the oxygen uptake
- Secondary Outcome Measures
Name Time Method sense of appetite 4 hours determination of the hormones ghrelin and GLP-1 in serum
Trial Locations
- Locations (1)
Faculty of Medicine and Health Sciences
🇸🇪Linköping, Sverige, Sweden
Faculty of Medicine and Health Sciences🇸🇪Linköping, Sverige, SwedenFredrik Nyström, MDContact+132237749fredrik.nystrom@regionostergotland.seFredrik H Nystrom, professorPrincipal Investigator