The Wound Etiology and Healing Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 743
- 试验地点
- 1
- 主要终点
- Time to wound healing
研究概览
简要总结
The purpose of the WE-HEAL Study is to help researchers use human tissue samples and health records to study the reasons why some patients heal quickly and some have problems healing wounds. All patients seen with an open wound or hidradenitis suppurativa are invited to participate. Information from this research may help to understand how to prevent and treat certain diseases.
研究设计
- 研究类型
- Observational
- 观察模型
- Ecologic Or Community
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 99 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Open wound or hidradenitis suppurativa
- •English speaking
- •Able to give informed consent
排除标准
- •Non-English speaking.
- •Unable to give informed consent
结局指标
主要结局
Time to wound healing
时间窗: 10 years
This prospective study will establish a biobank for collection of residual biopsy tissue discarded after debridement, and collection of other biospecimens at the discretion of the investigators including wound fluid and serum samples. Patients will also permit linking of biosamples to clinical outcomes data. Using a primary outcome of wound healing we will compare biomarkers on tissue, serum and wound fluid from patients with non-healing ulcers and hidradenitis to identify angiogenic and vasculogenic pathways that are dysregulated in patients with wound healing problems.
次要结局
未报告次要终点
研究者
Victoria Shanmugam, MD
Professor
George Washington University