PRactice of Ventilation and Adjunctive Therapies in COVID-19 Patients.

Completed

• Conditions: COVID-19 Acute Respiratory Distress Syndrome

• Registration Number: NCT05954351
• Lead Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Brief Summary

PRactice of Ventilation and Adjunctive Therapies in COVID-19 Patients. An observational study of ventilation practice and adjunctive therapies in critically ill, invasively ventilated COVID-19 patients during the first and second surge of COVID-19 in the Netherlands.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-05-01
• Primary Completion: 2023-07-01
• Study Completion: 2023-07-01
• Study First Submitted: 2023-07-19
• Study First Submitted QC: 2023-07-19
• Study First Posted: 2023-07-20
• Status Verified: 2024-07
• Last Update Submitted: 2024-07-01
• Last Update Posted: 2024-07-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 2465

Inclusion Criteria

• receiving invasive ventilation or high-flow nasal oxygen for COVID-19 for SARS-CoV-2
• admitted to one of the ICUs of the participating hospitals

Exclusion Criteria

• none

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
ICU mortality	90 days from inclusion

Secondary Outcome Measures

Name	Time	Method
28-day ventilator free days	90 days from inclusion
Duration of ventilation	90 days from inclusion
28-day, 90-day mortality	90 days from inclusion
ICU and hospital length of stay	90 days from inclusion

Trial Locations

Locations (1)

Academic Medical Center; 🇳🇱 Amsterdam, Noord-Holland, Netherlands