NL-OMON49762
Not yet recruiting
Phase 2
Combination of chemoTherapy aNd chemoradioTherapy for adenocarcinoma of the OESophagus and gastro-oesophageal junction with limited metastatic disease - TNT-OES-1 TRIAL - TNT-OES-1 TRIA
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Erasmus MC, Universitair Medisch Centrum Rotterdam
- Enrollment
- 20
- Status
- Not yet recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •\- adenocarcinoma of the esophagus or gastro\-esophageal junction with limited
- •but distant retroperitoneal and/or supraclavicular lymphatic dissemination
- •and/or maximum of 4 oligo metastases
- •\- resectable primary esophageal tumor
- •\- age 18\-75
- •ECOG performance status 0\-1
- •No prior radiotherapy or chemotherapy
Exclusion Criteria
- •Polyneuropathy grade 1 or higher
- •Secondary primary cancer
- •Clinically significant cardiac disease (e.g. symptomatic coronary artery
- •disease or myocardial infarction within last 12 months)
- •Clinically significant pulmonary disease (Forced expiratory volume in 1 second
Outcomes
Primary Outcomes
Not specified
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