Autologous Platelet Gel in Wound Healing of Coronary Artery Bypass Grafting (CABG) Patients

Not Applicable

Withdrawn

• Conditions: Infection; Wounds
• Interventions: Biological: autologous platelet gel

• Registration Number: NCT00672672
• Lead Sponsor: University of Nebraska

Brief Summary

This study will determine if autologous platelet gel (APG) on sternal incision and conduit sites will improve wound healing and decrease infection in coronary artery bypass grafting surgery patients.

Detailed Description

The purpose of this study is to determine if the use of autologous platelet gel (APG) on sternal incision and conduit sites will improve wound healing and decrease the incidence of infection in patients undergoing coronary artery bypass grafting surgery

Study Timeline

• Study First Submitted: 2008-05-02
• Study First Submitted QC: 2008-05-05
• Study First Posted: 2008-05-06
• Study Start: 2009-01-13
• Primary Completion: 2010-01-06
• Study Completion: 2010-01-06
• Status Verified: 2023-08
• Last Update Submitted: 2023-08-11
• Last Update Posted: 2023-08-15

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• Any patient who meets criteria and consents to undergo a CABG procedure involving conduit sites and consents to this study.

Exclusion Criteria

• Any patient, after inclusion, whom is later determined to have had on-going therapy that could influence wound healing such as radiation or chemotherapy, extensive steroid use, or accidental trauma such as burns, etc.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Control (No platelet gel)	autologous platelet gel	Participants do not receive platlet gel.
Platelet Gel	autologous platelet gel	Participants receive platlet gel.

Primary Outcome Measures

Name	Time	Method
Healing and infection of surgical sites	30 days	The surgical sites will be assessed for degree of healing and signs and symptoms of infection on post-op days one and three and during the patients' follow up visits in the clinic.