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Fluorescence and reflectance spectroscopic imaging scan for detection of cervical neoplasia

Completed
Conditions
Cervical intraepithelial neoplasia
precancerous cervical cells
10013364
Registration Number
NL-OMON41942
Lead Sponsor
niversitair Medisch Centrum Sint Radboud
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
152
Inclusion Criteria

Age >=18 years
Requiring colposcopic evaluation or requiring control pap-smear after previous treatment or with a watchful waiting policy

Exclusion Criteria

Currenty pregnant or pregnancy in the last 3 months
Currently undergoing treatment for cervical cancer
Current menstruation
Previous pelvic radiotherapy
High-grade cervical smear

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>The main study parameters are sensitivity, specificity, positive predictive<br /><br>value and negative predictive value of the multimodal hyperspectroscopy<br /><br>cervical scan to detect high grade cervical intraepithelial neoplasia. The<br /><br>result of the cervical scan will be compared to the result of the hrHPV test. </p><br>
Secondary Outcome Measures
NameTimeMethod
<p>Secundary study parameters are: ease of use of the cervical scan and adverse<br /><br>events of the scan for the patient. Duration of the scan and additional time<br /><br>needed for the appointment because of the scan will also be evaluated.</p><br>
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