The Relationship Between Preoperative Nutritional and Inflammatory Markers and Early Postoperative Clinical Outcomes in Patients Undergoing Bariatric Surgery
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 86
- 试验地点
- 1
- 主要终点
- Occurrence of Postoperative Complications Within 72 Hours
研究概览
简要总结
This prospective observational study aims to evaluate whether preoperative immune-nutritional markers-specifically the Prognostic Nutritional Index (PNI), HALP score, Neutrophil-to-Lymphocyte Ratio (NLR), and C-Reactive Protein (CRP)-can predict early postoperative clinical outcomes such as time to oral intake, mobilization, complications, and length of hospital stay in patients undergoing elective laparoscopic sleeve gastrectomy.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age between 18 and 65 years
- •Body mass index (BMI) ≥ 35 kg/m²
- •Scheduled for elective laparoscopic sleeve gastrectomy
- •Availability of complete preoperative laboratory test results
- •Signed informed consent
排除标准
- •Severe hepatic or renal dysfunction
- •Presence of active infection
- •History of immunosuppressive therapy or hematologic malignancy
- •Need for intensive care unit (ICU) admission within the first 72 hours postoperatively
- •Preoperative administration of albumin or blood products
结局指标
主要结局
Occurrence of Postoperative Complications Within 72 Hours
时间窗: Up to 72 hours after surgery
Complications such as fever, surgical site infection, nausea/vomiting, hypotension, or need for reintervention will be recorded during the first 72 hours after laparoscopic sleeve gastrectomy. The association between preoperative nutritional and inflammatory scores (PNI, HALP, NLR, CRP) and complication occurrence will be evaluated.
次要结局
未报告次要终点
研究者
İlke Dolgun
Assoc. prof
Istinye University