An observational retrospective/prospective study of treatment strategies for ovarian germ cell and sex cord-stromal tumors in Germany(Current Ovarian geRm cell and SEx cord Tumor Treatment strategies)

Recruiting

• Conditions: C56; D07.3; D39.1; Malignant neoplasm of ovary; Other and unspecified female genital organs; Ovary

• Registration Number: DRKS00005789
• Lead Sponsor: niversitätsfrauenklinik Freiburg

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2016-02-12
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 400

Inclusion Criteria

Female patients (any age) who were diagnosed with malignant OGCTs and SCSTs (ICD C56, D07.3 and D 39.1) or dermoid cysts with immature/malign somatic components starting from January 2001 to 2011. All centers must be able to provide paraffin embedded tumor slides for each patient for central pathology re-assessment and if possible tumor blocks.

Exclusion Criteria

Benign OGCTs including teratomas, benign cystic mature teratomas (dermoid cysts).

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Overall survival (OS) and progression-free survival (PFS), calculated from the day of diagnosis (day of surgery, PFS and OS after relapse are calculated from the day of relapse) in relation to treatment strategies for OGCTs and SCSTs

Secondary Outcome Measures

Name	Time	Method
Reproductive outcomes (pregnancy rates and births), quality of life, sexual life in relation to treatment strategies for OGCTs and SCSTs. <br>