Evaluation and Treatment Strategy Development of Coronary Heart Disease Guided by Optical Coherence Tomography Based on Multimodal Deep Learning
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Coronary Disease
- Sponsor
- Xiang Ma
- Enrollment
- 2000
- Primary Endpoint
- MACE
- Status
- Not yet recruiting
- Last Updated
- last year
Overview
Brief Summary
This is a retrospective, multicenter, observational study aimed at assessing stent apposition for coronary stent implantation by an optical coherence tomography system constructed by deep learning algorithms and evaluating the prognosis of patients after stent implantation in conjunction with multimodal diagnostic and therapeutic information.
Detailed Description
In this study, we planned to retrospectively collect 2,000 subjects who underwent optical coherence tomography-guided percutaneous coronary stent implantation with an optical coherence tomography system constructed by a deep learning algorithm from 3 centers to assess stent apposition for coronary stent implantation, and to classify subjects into a group with poor stent apposition (axial distance \>400 μm or length \>1 mm) and a group with good stent apposition. All subjects were followed up within 12 months after the procedure.
Investigators
Xiang Ma
professor
First Affiliated Hospital of Xinjiang Medical University
Eligibility Criteria
Inclusion Criteria
- •Age ≥20 years old;
- •Angiography was performed, and OCT imaging of criminal blood vessels was performed before intervention;
- •Type of coronary heart disease: Unstable angina pectoris (UA), ST elevation myocardial infarction (STEMI) And non-ST elevation myocardial infarction (NSTEMI);
Exclusion Criteria
- •Lack of medical records;
- •Failure to complete follow-up;
- •Previous coronary artery bypass grafting;
- •Severe liver or kidney insufficiency;
- •Infectious diseases, malignancies and bleeding diseases;
- •OCT image quality was caused by large thrombus volume or residual blood in lumen and percutaneous coronary angiography Poor and further excluded.
Outcomes
Primary Outcomes
MACE
Time Frame: Post-procedure within 1 year
Patients were followed up within 1 year after OCT and PCI. The follow-up included major adverse cardiac events: All causes were death, recurrent myocardial infarction, target vessel reconstruction, and stent thrombosis.