NCT04088279Unknown不适用
Novel Quantitative Magnetic Resonance Imaging (MRI) Measures in the Assessment and Follow-up of Patients With Pulmonary Hypertension (PH)
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Fractions (% area of lung imaged)
研究概览
简要总结
A prospective study of the use of two novel MRI techniques (oxygen-enhanced and fourier decomposition MRI) in the initial diagnosis and follow-up of patients with Pulmonary Hypertension. The investigators believe these techniques may present a novel set of imaging biomarkers that may be used for risk stratification, prediction of treatment response and longitudinal disease monitoring. The reserach MRI is in addition to standard of care and will not affect treatment decisions.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Confirmed diagnosis of Pulmonary Hypertension.
- •Age 18 and over.
排除标准
- •Standard contra-indications to MRI (as per NHS MRI safety questionnaire).
- •Not medically fit for transfer to MRI.
- •Patient judged inappropriate for involvement in study by clinical team e.g. secondary to emotional burden of recent diagnosis.
结局指标
主要结局
Fractions (% area of lung imaged)
时间窗: Baseline and 3-6 months
Delta pO2 max (mmHg)
时间窗: Baseline and 3-6 months
Wash in and wash out time constants (min)
时间窗: Baseline and 3-6months
Signal Intensity Change (%)
时间窗: Baseline and 3-6months
次要结局
未报告次要终点
研究者
研究点 (1)
Loading locations...
相似试验
撤回
不适用
Comparison of Quantitative MRI Perfusion Methods With Quantitative PET Perfusion ImagingMRI ScansNCT02608944University of Utah
Unknown
不适用
Development and Validation of Novel MRI Methods for the Detection of Prostate Cancer AggressivenessProstate CancerNCT02545881Turku University Hospital200
终止
不适用
Study of New Magnetic Resonance MethodsHealthyNCT00001844National Institutes of Health Clinical Center (CC)99
已完成
不适用
Refinement and Assessment of New Magnetic Resonance Imaging (MRI) Technologies for Vascular, Abdominal, and Pelvic ExamsHealthyNCT00738712University of Michigan20
已完成
不适用
New Magnetic Resonance Imaging and Spectroscopy Software in the Improvement of Image QualityHematopoietic and Lymphoid Cell NeoplasmMalignant Solid NeoplasmNCT03980535M.D. Anderson Cancer Center273