Bioavailability of Potassium From Potatoes and Potassium Gluconate

Not Applicable

Completed

• Conditions: Potassium Bioavailability; Blood Pressure

• Registration Number: NCT01881295
• Lead Sponsor: Purdue University

Brief Summary

This study is designed to compare the effect of sources of potassium on uptake and the effect of potassium on blood pressure.

Detailed Description

The study will compare uptake of potassium from three different doses and sources; supplements (720, 1440 and 2160 mg) potatoes (720, 1440 and 2160 mg) or French fries (2160 mg).

During 9 phases, participants will consume a controlled diet with the supplements, potato or french fries (every other week for 5 days). On the 4th day, blood and urine samples will be taken to monitor potassium uptake and excretion. Measures of blood pressure will be analyzed at defined time points throughout the intervention.

Study Timeline

• Study Start: 2013-03-01
• Study First Submitted: 2013-06-17
• Study First Submitted QC: 2013-06-17
• Study First Posted: 2013-06-19
• Primary Completion: 2014-08
• Study Completion: 2014-12
• Status Verified: 2018-05
• Last Update Submitted: 2018-05-03
• Last Update Posted: 2018-05-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 45

Inclusion Criteria

• Able to adhere to the visit schedule, protocol requirements and available to complete the study
• Normotensive men and women
• Aged 20-60 years
• BMI of 15-35

Exclusion Criteria

• Medication to treat hypertension or hypotension
• Medication known to affect electrolyte metabolism or contain high levels of potassium or sodium
• smoke cigarettes or use illegal drugs
• Hypertension or hypotension
• Diseases known to affect potassium metabolism
• Pregnant
• Allergic to nuts

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
Bioavailability of Potassium	5 days	After 4 days of acclimation to the supplementation, absorption of potassium will be measured.

Secondary Outcome Measures

Name	Time	Method
Blood Pressure Response to Potassium	6 days	Differences in blood pressure will be measured between levels of potassium consumption.

Trial Locations

Locations (1)

Purdue University; 🇺🇸 West Lafayette, Indiana, United States