The effect of transcranial direct current stimulation on stroke

Not Applicable

Conditions: patients with unilateral ischemic stroke having a paralyzed upper limb.
I63.9
Cerebrovascular accident-ischemic

Registration Number: IRCT20130416013027N3

Lead Sponsor: Guilan University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 50

Inclusion Criteria

age between 18 and 65 years
unilateral ischemic stroke in middle cerebral artery
upper limb plegia
stroke onset and intervention starting interval from 2 weeks to 1 month
National institude of health stroke scale (NIHSS) score less than 20 at the time of intervention

Exclusion Criteria

cognitive state score in mini mental score examination less than 24
Conditions which are not compatible to safety guidelines of brain stimulation
those with tDCS contraindication , such as pregnant patients, patients with metal implants , those having a heart pacemaker
drug history of psychoactive drugs or CNS effective drugs except tPA and medications used for stroke routine treatment .
substance abusers
Concurrent psychiatric and other non-stroke neurological disease
The use of medications blocking voltage-dependent calcium and sodium channels
History or existence of scalp eczema
Clinical instability

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Motor function of upper limb. Timepoint: baseline/before intervention, the final session of intervention, three months after final therapy. Method of measurement: Medical Research Council Scale for Muscle Strength (MRC).

Secondary Outcome Measures

Name	Time	Method
eurological deficit severity. Timepoint: baseline and final session of intervention, three months after final therapy. Method of measurement: National institute of health stroke scale (NIHSS).