Dexamphetamine effects on the perceptions of visual, auditory, tactile and multimodal illusions in healthy volunteers
- Conditions
- This is a dexamphetamine challenge study in healthy volunteers as a model for studying dopaminergic mechanisms in psychosesMental Health - Schizophrenia
- Registration Number
- ACTRN12615000619549
- Lead Sponsor
- Mathew Martin-Iverson
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 66
Healthy people >17 and <60 years of age
1.Heart or severe blood vessel disease,
2.High blood pressure (> 180/90 mm Hg),
3.Glaucoma,
4.Hyperthyroidism (overactive thyroid),
5.Tics (muscle twitching usually in the face or shoulders),
6.Sensitivity to dexamphetamine or sympathomimetic amines,
7.Any degenerative disease of the nervous system,
8.Epilepsy, or other neurological disorder, including head injury.
9.Tourette's syndrome or a family history of this disorder,
10.A psychiatric or psychological problem for which they are receiving treatment (schizophrenia, depression, anxiety, etc),
11.A serious medical problem for which they are receiving treatment (cardiovascular disorders, respiratory disorders, etc),
12.Had or are currently receiving treatment for substance abuse,
13.A family history of schizophrenia in first-degree relatives (parents, children or siblings),
14.Previously experienced hypersensitivity to dexamphet-amine,
15.Used any drug including alcohol or any illicit drug within 24 hours of each testing session,
16.Used caffeine on the day of each testing session,
17.Current prescription medication that you are taking other than contraceptives or acne medication
18.Used over-the-counter medication in the 48 hours before each testing session
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method