To evaluate efficacy of local Amikacin therapy as an adjuvant to parental antibiotic in control of SSI compared to parental antibiotics alone in a rural hospital
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Post-surgical infections are becoming a very common entity that can be easily avoided with proper usage of local antibiotic(Amikacin) along with parental antibiotics, we expect that the ASEPSIS scoring system will aid in proving the efficacy of local amikacin on operated site to prevent SSI
研究概览
简要总结
It is a prospective interventional (simple randomized control study ) aimed at evaluating the efficacy of local use of amikacin therapy as an adjuvant to a parental antibiotic in control of SSI compared to parental antibiotics alone. SSI is becoming a fairly common occurrence in tertiary care hospitals which can be avoided and provide better prognostic relief and less hospital stay for the patient. ASEPSIS scoring system is used to differentiate and compare groups among local amikacin therapy and parental antibiotic versus parental antibiotics alone, using which a definitive comparative analysis can be derived for better clinical outcome
The current study aims to definitely prove the efficacy of using local amikacin therapy as an adjuvant to parental antibiotics in control of SSI compared to parental antibiotics alone in a rural hospital.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18.00 Year(s) 至 75.00 Year(s)（—）
- 性别
- All
入选标准
- •All patients presenting to AVBRH with a case of clean and elective surgeries for abdominal surgeries 2) Patients between 18-74 years of age.
排除标准
- •Extremes of age less than 18 yrs and greater than 75yrs 2) Patients who are on immune-suppressants, chemo/radiotherapy, steroids other serious pre-existing cardiovascular, pulmonary, and immunological disease.
- •Uncontrolled diabetic patients 4) Local infection.
结局指标
主要结局
Post-surgical infections are becoming a very common entity that can be easily avoided with proper usage of local antibiotic(Amikacin) along with parental antibiotics, we expect that the ASEPSIS scoring system will aid in proving the efficacy of local amikacin on operated site to prevent SSI
时间窗: 2 years
次要结局
- To evaluate efficacy of local Amikacin therapy as an adjuvant to parental antibiotic in control of SSI compared to parental antibiotics alone in a rural hospital(2 years)
研究者
Abhiram Chadive
Datta Meghe Institute of Higher Education and Research