NCT04935021RecruitingPhase 4
Clinical Study Protocol of Transthyroxine Protein Amyloidosis Cardiomyopathy and Its Gene Carriers
Second Affiliated Hospital, School of Medicine, Zhejiang University1 site in 1 country100 target enrollmentStarted: June 1, 2021Last updated:
Conditions
Interventions
Drugs
Trial Snapshot
- Phase
- Phase 4
- Status
- Recruiting
- Sponsor
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- Rate of cardiovascular death, myocardial infarction, and stroke
Study Overview
Brief Summary
In this study, patients with ATTR-CM or gene carriers were selected to study the diagnosis and treatment, and long-term follow-up was conducted.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to 80 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Patients and gene carriers of ATTR-CM confirmed in the Second Affiliated Hospital of Zhejiang University School of Medicine, regardless of gender, age 18-90 years old;
- •Patients who have the ability to understand the test and can cooperate with investigators
Exclusion Criteria
- •Patients who unable to understand or unwilling to fill in informed consent forms or follow visitors
Arms & Interventions
ATTR-CM
Experimental
Patients or Gene carrier
Intervention: ATTR-CM (Drug)
Outcomes
Primary Outcomes
Rate of cardiovascular death, myocardial infarction, and stroke
Time Frame: 10 year
Primary Outcome
Secondary Outcomes
No secondary outcomes reported
Investigators
Study Sites (1)
Loading locations...
Similar Trials
Completed
Not Applicable
Prevalence and Characteristics of Transthyretin Amyloidosis in Patients With Left Ventricular Hypertrophy of Unknown EtiologyTransthyretin Amyloidosis Cardiomyopathy (ATTR-CM)NCT03842163Pfizer812
Recruiting
Not Applicable
Thailand ATTR-CM RegistryTransthyretin Amyloid Cardiomyopathy (ATTR-CM)NCT06338696Mahidol University105
Completed
Phase 2
Recombinant Thyrotropin PET-CT Fusion Scanning in Thyroid CancerThyroid CancerNCT00181168Johns Hopkins University63
Recruiting
Not Applicable
NatiOnal Referral cenTEr Study of Transthyretin Amyloid Cardiomyopathy(ATTR) Patients on TafamidisAmyloidosis CardiacATTR Amyloidosis Wild TypeAmyloidosisNCT06251778Paolo Milani200
Completed
Not Applicable
Cost-effectiveness of TPMT PharmacogeneticsInflammatory Bowel DiseasesUlcerative ColitisCrohn DiseaseNCT00521950ZonMw: The Netherlands Organisation for Health Research and Development853