Can knee muscle activation be altered using modified clinical exercises in patients with osteoarthritis?

Phase 2

• Conditions: Knee joint osteoarthritis; Musculoskeletal - Osteoarthritis

• Registration Number: ACTRN12613000448741
• Lead Sponsor: Murdoch University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-04-19
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Patient Group:
Medial compartment tibiofemoral compartment osteoarthritis scored as Kellgren and Lawrence Grade 3 or 4

Control Group
Asymptomatic

Exclusion Criteria

Patient Group:
Any neurological condition
Rheumatic disease other than osteoarthritis
Significant involvement of the lateral tibiofemoral compartment (Kellgren and Lawrence Grade 2 or higher)
Any other current lower limb injuries

Control Group
Any neurological condition
Rheumatic disease other than osteoarthritis
Osteoarthritis in the lower limb
Any other current lower limb injuries

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Co-contraction ratio between medial and lateral muscle groups. Muscle activation during the exercises will be collected with electromyography. Co-contraction ratios will be calculated post-hoc using custom software. [During the performance of the exercise. Electromyography records muscle activations during the performance of a task.]

Secondary Outcome Measures

Name	Time	Method
Total activation of all muscles crossing the knee. Muscle activation during the exercises will be collected with electromyography. Total activation will be calculated post-hoc using custom software. [During the performance of the exercise. Electromyography records muscle activations during the performance of a task.]