Randomised controlled clinical trial to study the effect of Rajikushthadi Lepa in Pama with special reference to scabies in school going children

According to Indian journal of paediatric dermatology prevalence of scabies in school going children in India is 11 percent. Developing resistance to commonly used drugs like permethrin underscores the need to explore alternative options for local applications.Rajikushthadi lep sounds promising with its kandughna (anti-itch) and kushthaghna (anti-dermatosis) properties, especially considering itching (kandu) is a characteristic feature in (Pama). Addressing itching is crucial in managing various skin conditions including those associated with Pama. Conducting research to evaluate the effectiveness of Rajikushthadi Lepa in treating Pama is crucial for expanding our understanding of traditional remedies and their applications in modern healthcare. By filling the knowledge gap, the study can provide valuable insights into the potential benefits of Rajikushthadi Lepa and its role in managing Pama. Including patients within the school-going age group (6-12 years) who fulfill the clinical diagnostic criteria for scabies, patients are selected irrespective of sex, socio-economic status, and community helps in achieving a diverse and representative sample, enhancing the generalizability of the study findings, written consent from parents ensures ethical compliance and transparency in the treatment process. SAMPLE SIZE using formula by Daniel 1999, the calculated sample size is 37. Simple Random Sampling technique will be used. Total 74 number of patients will be selected and divided into two groups, named as Group A (trial group) and Group B (Control group).Rajikushthadi lepa Group A (trial group) and Mulakbijadi lep Group B(Control group) will be given to patients.Trial and control drugs will be purchased from GMC certified pharmacy. Both drugs will be administered in Lepa form for 11 days. All SOP of Lepa Vidhi will be strictly followed during and after treatment. Observations will be done on day 0, day 3 and day 7. Result of study will drawn on basis of criteria of assessment and statistical analysis.Discussion will be done on the basis of observations and result obtained during the treatment.Summary will be drawn and whole thesis work will be summarized. Conclusion will be drawn strictly on basis of statistical analysis and will be unbiased