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临床试验/NCT07138456
NCT07138456尚未招募不适用

Clinical Severity of Dental Fluorosis and Associated Risk Factors Among a Group of Children in a Rural Region, Dendera Center in Egypt: A Cross-Sectional Study

Cairo University1 个研究点 分布在 1 个国家目标入组 231 人开始时间: 2026年2月20日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
231
试验地点
1
主要终点
Clinically evident dental fluorosis in permanent incisors (prevalence)

研究概览

简要总结

The goal of our observational study is evaluation of the clinical severity of dental fluorosis and associated risk factors among a group of children (8-12 years old) in a rural region, Dendera center, Egypt.

The main question it aims to answer is:

What is the clinical severity of dental fluorosis and associated risk factors among a group of children (8-12 years old) in a rural region, Dendera center, Egypt?

详细描述

Fluoride has a dual impact, it can be beneficial for dental health when consumed at optimal levels, but excessive intake can lead to a condition known as dental fluorosis (DF).

Dental fluorosis, which is particularly common among children and young individuals, is a developmental enamel defect caused by excessive fluoride exposure during the critical stages of tooth formation. This condition affects both the appearance and structure of the enamel.

The severity of dental fluorosis depends on various factors, including fluoride concentration in drinking water, daily intake, duration of exposure, and climatic conditions.

Epidemiological studies indicate that fluorosis can affect individuals across different age groups, with cases ranging from mild dental fluorosis to severe skeletal fluorosis. Children are particularly vulnerable to its harmful effects, which are often irreversible.

In rural areas, groundwater serves as the primary source of drinking water due to limited access to treated water supplies.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Cross Sectional

入排标准

年龄范围
8 Years 至 12 Years(Child)
性别
All
接受健康志愿者

入选标准

  • 未提供

排除标准

  • 未提供

结局指标

主要结局

Clinically evident dental fluorosis in permanent incisors (prevalence)

时间窗: Baseline (during the initial clinical examination of the child)

Clinical examination (using a probe and mouth mirror in bright daily life, using ICMR index which have the following scores 0: no fluorosis /1: mild fluorosis _ 2: moderate fluorosis / 3: severe fluorosis)

次要结局

  • Clinically evident dental fluorosis in all permanent teeth present other than permanent incisors (prevalence)(Baseline (during the initial clinical examination of the child))
  • Risk factors of dental fluorosis(baseline (upon enrollment, after parents complete the questionnaire))
  • Severity of dental fluorosis(Baseline (during the initial clinical examination of the child))

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Gihad Mohamed Abdelraheem Abdelmajeed

Gihad Mohamed Abdelraheem Abdelmajeed

Cairo University

研究点 (1)

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