Clinical Severity of Dental Fluorosis and Associated Risk Factors Among a Group of Children in Rural Region, Dendera Center in Egypt
- Conditions
- Dental Fluorosis
- Registration Number
- NCT07138456
- Lead Sponsor
- Cairo University
- Brief Summary
The goal of our observational study is evaluation of the clinical severity of dental fluorosis and associated risk factors among a group of children (8-12 years old) in a rural region, Dendera center, Egypt.
The main question it aims to answer is:
What is the clinical severity of dental fluorosis and associated risk factors among a group of children (8-12 years old) in a rural region, Dendera center, Egypt?
- Detailed Description
Fluoride has a dual impact, it can be beneficial for dental health when consumed at optimal levels, but excessive intake can lead to a condition known as dental fluorosis (DF).
Dental fluorosis, which is particularly common among children and young individuals, is a developmental enamel defect caused by excessive fluoride exposure during the critical stages of tooth formation. This condition affects both the appearance and structure of the enamel.
The severity of dental fluorosis depends on various factors, including fluoride concentration in drinking water, daily intake, duration of exposure, and climatic conditions.
Epidemiological studies indicate that fluorosis can affect individuals across different age groups, with cases ranging from mild dental fluorosis to severe skeletal fluorosis. Children are particularly vulnerable to its harmful effects, which are often irreversible.
In rural areas, groundwater serves as the primary source of drinking water due to limited access to treated water supplies.
This dependence on groundwater increases the risk of prolonged fluoride exposure, particularly among children, whose developing teeth are more susceptible to fluorosis.
While several studies have documented the prevalence of dental fluorosis globally, there is a lack of data on its prevalence in rural areas of Upper Egypt, where groundwater is a key water source.
This knowledge gap highlights the need for localized research to assess the extent of the issue and develop targeted interventions.
Therefore, a cross-sectional study will be conducted to determine the prevalence and severity of dental fluorosis and identify associated risk factors among children in a rural area of the Dendera district, Qena governorate, Upper Egypt.
Recruitment & Eligibility
- Status
- NOT_YET_RECRUITING
- Sex
- All
- Target Recruitment
- 231
Not provided
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Clinically evident dental fluorosis in permanent incisors (prevalence) Baseline (during the initial clinical examination of the child) Clinical examination (using a probe and mouth mirror in bright daily life, using ICMR index which have the following scores 0: no fluorosis /1: mild fluorosis _ 2: moderate fluorosis / 3: severe fluorosis)
- Secondary Outcome Measures
Name Time Method Clinically evident dental fluorosis in all permanent teeth present other than permanent incisors (prevalence) Baseline (during the initial clinical examination of the child) Clinical examination (using a probe and mouth mirror in bright daily life, using ICMR index which have the following scores 0: no fluorosis /1: mild fluorosis _ 2: moderate fluorosis / 3: severe fluorosis)
Risk factors of dental fluorosis baseline (upon enrollment, after parents complete the questionnaire) Multiple choice questions (questionnaire answered by the children's parents with multiple choice questions).
Severity of dental fluorosis Baseline (during the initial clinical examination of the child) Scoring (0-3) according to Indian Council of Medical Research (ICMR) index which have the following scores 0: no fluorosis /1: mild fluorosis _ 2: moderate fluorosis / 3: severe fluorosis.
Trial Locations
- Locations (1)
Dendera region
🇪🇬Cairo, Qena, Egypt
Dendera region🇪🇬Cairo, Qena, Egypt