CTRI/2022/02/040289尚未招募不适用
Preoperative nebulization with Magnesium sulfate versus Ketamine for prevention of endotracheal tube induced postoperative sore throat-A prospective,randomized,comparative clinical study
SSG Hospital Vadodara1 个研究点 分布在 1 个国家目标入组 144 人开始时间: 2022年2月15日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 144
- 试验地点
- 1
- 主要终点
- To compare the incidence and severity of sorethroat at 4th postoperative hour.
研究概览
简要总结
This study will be carried out at government medical college,SSG Hospital,Vadodara. Overall purpose of this study is to compare the efficacy of nebulised ketamine versus nebulised magnesium sulfate for attenuation of postoperative sorethroat in patients undergoing general anaesthesia with endotracheal intubation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Other
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Patients posted for elective surgery under General anaesthesia requiring intubation and expected to last for less than three hours 2.ASA status I, II,III 3.Mallampatti airway assessment of Grade I and II.
排除标准
- •Patients who refuse to give consent 2)Anticipated difficult airway or Mallampatti Grade III & IV 3)Preoperative sore throat.
- •Active upper respiratory tract infections 5)Procedures requiring perioperative nasogastric tube placement or throat packing.
- •Patients with a high risk of aspiration.
- •Surgery involving oral cavity,nasopharynx, larynx or neck region 8)History of allergies/ bronchial asthma/ Chronic obstructive pulmonary disease 9)Surgery in prone position 10)Pregnant women.
结局指标
主要结局
To compare the incidence and severity of sorethroat at 4th postoperative hour.
时间窗: 4th postoperative hour.
次要结局
- 1) To compare the incidence and severity of sorethroat at 0, 2nd,6th,12th and 24th postoperative hours(2) To compare the incidence and severity of postoperative hoarseness of voice and cough)
研究者
研究点 (1)
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