Comparison of Use of two drugs taken through nose via special device before operation (nebulisation) for prevention of sorethroat which may occur in postoperative period due to insertion of a tube in windpipe.

Not yet recruiting

• Conditions: Other general symptoms and signs,

• Registration Number: CTRI/2022/02/040289
• Lead Sponsor: SSG Hospital Vadodara

Brief Summary

This study will be carried out at government medical college,SSG Hospital,Vadodara. Overall purpose of this study is to compare the efficacy of nebulised ketamine versus nebulised magnesium sulfate for attenuation of postoperative sorethroat in patients undergoing general anaesthesia with endotracheal intubation.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2022-02-13
• Study Start: 2022-02-15

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 144

Inclusion Criteria

1.Patients posted for elective surgery under General anaesthesia requiring intubation and expected to last for less than three hours 2.ASA status I, II,III 3.Mallampatti airway assessment of Grade I and II.

Exclusion Criteria

• 1)Patients who refuse to give consent 2)Anticipated difficult airway or Mallampatti Grade III & IV 3)Preoperative sore throat.
• 4)Active upper respiratory tract infections 5)Procedures requiring perioperative nasogastric tube placement or throat packing.
• 6)Patients with a high risk of aspiration.
• 7)Surgery involving oral cavity,nasopharynx, larynx or neck region 8)History of allergies/ bronchial asthma/ Chronic obstructive pulmonary disease 9)Surgery in prone position 10)Pregnant women.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the incidence and severity of sorethroat at 4th postoperative hour.	4th postoperative hour.

Secondary Outcome Measures

Name	Time	Method
1) To compare the incidence and severity of sorethroat at 0, 2nd,6th,12th and 24th postoperative hours	2) To compare the incidence and severity of postoperative hoarseness of voice and cough

Trial Locations

Locations (1)

SSG Hospital; 🇮🇳 Vadodara, GUJARAT, India

SSG Hospital

🇮🇳Vadodara, GUJARAT, India

Dr Darshna Dharmendra Patel

Principal investigator

9925013155

dr.darshna1968@yahoo.com