Attention control training for infants at risk of ADHD

Not Applicable

Completed

• Conditions: Infants at risk for Attention Deficit Hyperactivity Disorder (ADHD); Mental and Behavioural Disorders

• Registration Number: ISRCTN37683928
• Lead Sponsor: Birkbeck College

Brief Summary

2016 Protocol article in https://www.ncbi.nlm.nih.gov/pubmed/28031039 protocol 2021 Results article in https://pubmed.ncbi.nlm.nih.gov/34930893/ (added 22/12/2021)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-06-22
• Study Completion: 2019-01-31
• Last Update Posted: 4 January 2022

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Inclusion criteria as of 12/01/2017
1. Infants will be under 14 months of age at enrolment;
2. Infants will have a first degree relative (an older sibling or a parent) with a clinical and/or research diagnosis of ADHD or a probable diagnosis of ADHD (assessed using DSM IV or V criteria). To note, depending on recruitment's rates, we may also recruit infants with an older sibling or parent with ASD;
3. Infants have agreed to take part in our affiliated STAARS project.

Screening procedure for ADHD probable diagnosis:
In order to maximise participation in the final months of recruitment the study team aim to introduce a targeted screening approach of specific populations. If an interested family will contact us about INTER-STAARS with a suspected diagnosis of ADHD for either a parent or child, we will assess eligibility using the following criteria:

Children
1. For children aged <6 years old:
A shortened version of the Conners Early Childhood (Conners, 2009) will be administered over the phone with a parent by a trained researcher. Cut-offs for inclusion will be:
1.1. Presence of 4 DSM-5 ADHD symptoms on either the inattention scale or the hyperactivity/impulsivity scale
1.2. Positive score on the impairment scale
2. For children aged >= 6 years old:
A shortened version of the Conners 3 (Conners, 2008) will be administered over the phone with a parent by a trained researcher. Cut-offs for inclusion will be:
2.1. Presence of 5 DSM-5 ADHD symptoms on either the inattention scale or the hyperactivity/impulsivity scale.
2.2. Positive score on the impairment scale.

Adults
1. A shortened version of the Conners Adult ADHD Rating Scale (CAARS, Conners, Erhart & Sparrow, 2003) will be administered over the phone by a trained researcher. The cut-off for inclusion will be:
1.1. Presence of 5 DSM-5 ADHD symptoms for either the hyperactivity/impulsivity or inattention scale.

Original inclusion criteria:
1. Infants will be under 12 months of age at enrolment;
2. Infants will have a first degree relative (an older sibling or a parent) with a clinical and/or research diagnosis of ADHD or a probable diagnosis of ADHD (assessed using DSM IV or V criteria). To note, depending on recruitment's rates, we may also recruit infants with an older sibling or parent with ASD

Exclusion Criteria

1. Serious medical or developmental conditions, such as epilepsy, heart conditions, cerebral palsy, intellectual disability
2. Significant uncorrected vision or hearing problems;
3. Eye-tracker not able to track infants’ eyes after four consecutive attempts as measured during the pre-training home assessment

Added 12/01/2017:
4. Down Syndrome in the older sibling

Study & Design

• Study Type: Interventional
• Study Design: Not specified