Renal Parenchymal Core Needle Biopsy

Not Applicable

Completed

• Conditions: Image-guided Biopsy; Kidney Glomerulus; Complications
• Interventions: Device: noncoaxial renal biopsy; Device: coaxial renal biopsy

• Registration Number: NCT02758535
• Lead Sponsor: Modarres Hospital

Brief Summary

Percutaneous image-guided parenchymal renal biopsy has been used to detect the different pathologies of renal parenchyma, to define the degree of reversible changes, and to define when the medical treatment fails. Percutaneous core needle renal biopsy has been reported to have a higher diagnostic yield compared to fine needle aspiration. Percutaneous core needle renal biopsy is usually based on tissue sampling under guidance of either sonography or computed tomography. Renal parenchymal biopsy can be done either with a coaxial or noncoaxial technique. In coaxial technique, the introducing needle is placed in the renal parenchyma; then, multiple tissue sampling can be performed throughout the same tract. Alternatively, in noncoaxial technique, biopsy needle is inserted repeatedly for each tissue sampling. Although there are some reports regarding the comparison of coaxial and noncoaxial methods of renal mass biopsy, comparison of the two methods in renal parenchymal biopsy has not yet been described in the literature. In this prospective study, the investigators sought to compare the procedural time and the complication rate of coaxial technique with those of noncoaxial technique in percutaneous renal parenchymal biopsy.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-03
• Primary Completion: 2015-06
• Study Completion: 2016-03
• Status Verified: 2016-04
• Study First Submitted: 2016-04-29
• Study First Submitted QC: 2016-04-29
• Last Update Submitted: 2016-04-29
• Study First Posted: 2016-05-02
• Last Update Posted: 2016-05-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 166

Inclusion Criteria

• impaired renal function
• proteinuria
• hematuria

Exclusion Criteria

• renal hydronephrosis
• chronic renal failure
• a history of renal cell carcinoma
• suspicious renal mass
• uncorrectable coagulopathy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Core needle biopsy with noncoaxial method	noncoaxial renal biopsy	The patients undergo renal biopsy with a noncoaxial Tru-Cut needle
Core needle biopsy with coaxial method	coaxial renal biopsy	The patients undergo renal biopsy with a coaxial Tru-Cut needle

Primary Outcome Measures

Name	Time	Method
complication ratio	within 48 hours after the procedure

Trial Locations

Locations (1)

Department of Radiology, Poursina Hospital, Guilan University of Medical Sciences; 🇮🇷 Rasht, Guilan, Iran, Islamic Republic of