Family-Based Treatment for Weight Restoration in Young Adults With Anorexia Nervosa
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 22
- 试验地点
- 2
- 主要终点
- Weight (BMI)
研究概览
简要总结
Temple University is conducting a National Institute of Health funded research study designed to develop and refine a family-based treatment manual for young adults with Anorexia Nervosa as well as assess the feasibility of this out-patient psychotherapy.
详细描述
Anorexia Nervosa (AN) is a serious psychiatric illness that occurs in an estimated 0.5 to 3.7% of women. The illness severely affects physical, emotional, and social functioning. The mortality rates associated with this severely disabling condition are higher than those for any other psychiatric disorder and substantially higher than those expected in the general population. Lower weight at presentation, longer illness duration, and alcohol abuse are associated with a higher risk of mortality.
Treatment-outcome for adult AN is poor with a quarter of adults with AN having poor outcome. In AN, promising outcomes are seen in family-based treatment (FBT) for adolescent patients who present between the ages of 12 to 18 with a short duration of illness. A manualized version of FBT has now been tested in several studies and case series, showing that well over 80% of participants had good or intermediate outcome at post-treatment. Despite its efficacy with adolescents, FBT has not been utilized with young adults.
The purpose of this study is to develop and refine FBT to promote weight gain in young adults with Anorexia Nervosa.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 30 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Meet DSM-IV criteria for AN (restricting/binge-purge type) (BMI 16.0-18.5)
- •Medically stable for outpatient treatment
- •Availability of at least one supportive adult of choice in study client's environment
- •Stable dose of psychotropic medication (8 weeks) for co-morbid condition
排除标准
- •Associated physical illness that necessitates hospitalization
- •Psychotic illness or other mental illness requiring hospitalization
- •Current dependence on drugs or alcohol
- •Physical conditions (e.g. diabetes mellitus, pregnancy) known to influence eating or weight
- •Previous Family-Based Treatment for Anorexia
结局指标
主要结局
Weight (BMI)
时间窗: 6 months of treatment
次要结局
- Changes in shape and weight concerns as measured with Eating Disorder Examination subscales(18 therapy sessions or 6 months of treatment)