Examining the Role of Pain in the Link Between Early Childhood Adversity and Psychopathology
- Conditions
- Interventions
- Registration Number
- NCT06445712
- Lead Sponsor
- Washington University School of Medicine
- Brief Summary
The goal of this study is to investigate the role of physical pain in the link between childhood adversity and later psychopathology. Children who are participating in a larger longitudinal study will be asked to submerge their hand in cold water and hold it in the cold water as long as possible. Participants will do this twice, once alone and once holding t...
- Detailed Description
This study will initiate a program of prospective research, linking early life adversity to both pain and psychopathology symptoms in the pre-adolescent period. This study will examine these links using an existing longitudinal sample of 6.5-9.5 year-old children experiencing familial stress. The project will examine the relationship between dysregulation an...
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 40
- Subjects who have been enrolled in our ongoing CARE study
- Subjects who have not participated in the CARE study
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Pain Assessment Parental Support Cold Pressor Task Children will submerge their hand in cold water and be asked to hold it in as long as possible. They will do this both alone and holding the hand of a parent (counterbalanced).
- Primary Outcome Measures
Name Time Method Pain Sensitivity 0-60 seconds after experiencing stimulus Self-reported score on the Visual Analogue Scale for Pain. Participants use a physical sliding scale to indicate how much pain they experienced \[ higher numbers are equal to more pain; (no pain (0-4 mm), mild pain(5-44 mm), moderate pain (45-74 mm), and severe pain (75-100 mm)\]
Pain Tolerance 0-120 seconds Time hand is held in cold water
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Laboratory for Child Brain Development
🇺🇸Saint Louis, Missouri, United States