Investigating the Effect of Intranasal Spray Containing Conditioned Medium from Umbilical Cord in Alzheimer's Disease

Phase 1

• Conditions: Mild to moderate phase ,Alzheimer's patients, Alzheimer Disease, AD, Dementia.; Diseases, Nervous System, Degenerative, Alzheimer's Disease, Late-onset, After the age of 65, AD, Dementia, Neurodegenerative, Central nervous system, CNS; G30.1

• Registration Number: IRCT20240131060870N1
• Lead Sponsor: Iran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 6 March 2024

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 9

Inclusion Criteria

Patients who have brain structural changes based on MRI and doctor's diagnosis, which confirms their Alzheimer's dementia.
Gender and Age: men and women between 60 and 85 Y.
Diagnosis of Mild to Moderate Alzheimer's dementia at least 6 months before the start of the study.
MMSE (Mini-Mental State Examination) Score: 10 and 24 at the time of starting the study

Exclusion Criteria

Cancer patients who have been diagnosed in the last 5 years.
Patients who cannot undergo MRI due to their condition.
People with mental disorders
Have diseases such as vitamin B12 deficiency, diabetes, hypo/hyperthyroidism, and hepatitis.
History of cell therapy in the last 6 months.
Subjects who have participated in another clinical study within 3 months before the start of this study.
History of brain neoplasm.

Study & Design

• Study Type: interventional
• Study Design: Not specified