Cognitive Health Promotion Project in the Community
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 发起方
- 入组人数
- 1,115
- 主要终点
- Change of Cognitive Function Measured by a Mini Mental State Examination Scores on a Scale According to Study Group
研究概览
简要总结
This study was based on baseline data derived from a large prospective study called the Suwon Project (SP), a cohort comprising random clustering samples of elderly people, all of whom are ethnic Koreans aged over 60 years.
详细描述
There is growing evidence supporting the protective effect of health behaviors against cognitive decline and dementia in older persons. With this increasing evidence and a better understanding of the underlying mechanisms, lifestyle modification is likely to be increasingly promoted as a convincing strategy for maintaining cognitive health in later life.
The study protocol included cognitive screening through the Korean version of the Mini-Mental State Examination (K-MMSE), which has been validated for the Korean-speaking population ({YW, 1997 #88}Kang YW et al., 1997), recording of the subject's medical history. A Korean study in the community defined the cut-off point of K-MMSE score during the screening of dementia as 17/18 points; the sensitivity and specificity of the findings were 91% and 86%, respectively ({YW, 1997 #88}Kim et al., 2003). Based on these results, we defined cognitive impairment (CI) as the group that had a K-MMSE score lower than 17, and not cognitive impairment (NCI) was defined as the group that had a K-MMSE score higher than 18.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 60 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •more than 60 years old
排除标准
- •those with a history of significant hearing or visual impairment that rendered participation in the interview difficult
- •those with a history of neurological disorders (e.g., stroke, Parkinson's disease, or active epilepsy)
- •those with psychiatric illness (e.g., schizophrenia, mental retardation, severe depression, or mania)
- •those taking psychotropic medications, or those with significant alcohol and other substance abuse.
结局指标
主要结局
Change of Cognitive Function Measured by a Mini Mental State Examination Scores on a Scale According to Study Group
时间窗: baseline and 18 months
The mini-mental state examination (MMSE) or Folstein test is a brief 30-point questionnaire test that is used to screen for cognitive impairment. It ranges from 0 to 30 points. The higher scores mean better outcome. It is also used to estimate the severity of cognitive impairment at a given point in time and to follow the course of cognitive changes in an individual over time, thus making it an effective way to document an individual's response to treatment. In the time span of about 10 minutes it samples various functions including arithmetic, memory and orientation.
次要结局
未报告次要终点
研究者
Chang Hyung Hong
Associate Professor
Ajou University School of Medicine