Memantine and Comprehensive, Individualized, Patient Centered Management of Alzheimer's Disease: A Randomized Controlled Trial: Further Study, Health Outcome
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- The total number of new medical conditions
研究概览
简要总结
This study is a retrospective review of the data collected in a previously completed randomized, controlled trial (RCT) entitled "Memantine and Comprehensive, Individualized, Patient Centered Management of Alzheimer's Disease: A Randomized Controlled Trial" (NCT00120874). As part of the previously completed RCT, participants with Alzheimer's Disease (AD) were randomly placed into one of two groups: memantine, or memantine plus an individualized management program consisting of home visits, educational sessions for caregivers, and a caregiver support group. Participants received the study intervention for 28 weeks; study follow-up lasted for 52 weeks.
The collected data from the existing study books from the 28 week treatment portion of the RCT will be carefully examined with respect to each of the research questions for the present retrospective study.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 50 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Previously participated in the "Memantine and Comprehensive, Individualized, Patient Centered Management of Alzheimer's Disease: A Randomized Controlled Trial" study.
排除标准
- 未提供
结局指标
主要结局
The total number of new medical conditions
时间窗: 28 weeks
Total number of hospitalizations
时间窗: 28 weeks
Total number of prescription medications taken throughout the study
时间窗: 28 weeks
Total number of days of hospice care
时间窗: 28 weeks
次要结局
- Total number of increases in psychotropic medications(28 weeks)
- Total number of decreases in psychotropic medications(28 weeks)
- Total number of analgesic medications taken during the study(28 weeks)
- Total number of cardiac medications taken during the study(28 weeks)
- Time to death(28 weeks)
- Differences in rate of fecal incontinence(28 weeks)
- Total number of psychotropic medications used(28 weeks)
- Total number arthritic and anti-inflammatory medications taken during the study(28 weeks)
- Total number of tests and procedures performed during the hospitalizations(28 weeks)
- Cause of death(28 weeks)
- Caregiver training and support in relation to mortality(28 weeks)
- Differences in rate of urinary incontinence(28 weeks)
- Total number of days hospitalized during the study(28 weeks)
- Reasons for hospitalizations and hospital diagnoses during the study(28 weeks)
- Changes in Functional Assessment Staging Disability Score (FAST-DS) at subsequent study visits post hospitalization(28 weeks)