Feasibility and efficacy of triplet regimen in transplant-ineligible NDMM patients
Not Applicable
- Conditions
- Multiple myeloma
- Registration Number
- JPRN-UMIN000027978
- Lead Sponsor
- Hyogo College of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Not provided
Exclusion Criteria
1) Smoldering or IgM myeloma, solitary plasmacytoma, plasma cell leukemia, POEMS syndrome, WM 2) CNS involvement 3) HIV+, HBs Ag+, or HCV Ab+ 4) Severe abnormality in the liver, kidney, cardiac, or pulmonary functions. Severe diabetes, hypertension, or infection. 5) Severe psychotic disorders.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method CR rate after the completion of the induction therapy
- Secondary Outcome Measures
Name Time Method 1) Response rate (VGPR, MRD negative) after the completion of the induction therapy 2) Adverse events 3) Quality of life at the time of the enrollment, after 6 courses of the induction therapy, and after the completion of the induction therapy