Investigating the Effects of Cardiac Rehabilitation eXercise Modalities on Physical and Mental Health Outcomes
- Conditions
- Coronary Artery Disease (CAD)
- Interventions
- Behavioral: Moderate Intensity Continuous Exercise TrainingBehavioral: Nordic WalkingBehavioral: High Intensity Interval Training
- Registration Number
- NCT02765568
- Lead Sponsor
- Ottawa Heart Institute Research Corporation
- Brief Summary
Coronary revascularization improves survival for patients with coronary artery disease. However,many patients are left with poor physical and mental health. Traditional cardiac rehabilitation involves moderate intensity continuous exercise (MICE). Alternatives to traditional cardiac rehabilitation programming may however provide superior understudied benefits to patients with poor physical and mental health. Nordic walking (NW) and high-intensity interval training (HIIT) are two examples of alternative programs for cardiac rehabilitation, which may provide superior physical and mental health benefits when compared to traditional MICE. The main purpose of this project is, therefore, to determine the short and long term physical and mental health benefits of alternative cardiac rehabilitation modalities, including NW and HIIT on exercise capacity, quality of life and depression after a 12-week program.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 135
- Patient with CAD who recently underwent PCI (within 2-10 weeks) PCI or coronary artery bypass grafting (within the last 18 weeks);
- Patient is referred to University of Ottawa Heart Institute cardiac rehabilitation program;
- Patient is able to walk independently
- Patient is willing to attend an onsite cardiac rehabilitation program twice weekly for 12 weeks;
- At least 40 years of age;
- Patient is willing and able to provide informed consent
- Currently participating in routine exercise training (>2x/week) and/or using Nordic Walking poles;
- Active infection or inflammatory condition;
- Over 75 years of age;
- Persistent or permanent atrial fibrillation;
- Pregnant, lactating or planning to become pregnant during the trial period;
- Unstable angina or established diagnosis of chronic obstructive pulmonary disease, severe mitral or aortic stenosis, or hypertrophic obstructive cardiomyopathy;
- Unable to read and understand English or French;
- Unwilling or unable to return for follow-up visit at weeks 12 and 26;
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Moderate Intensity Continuous Exercise Moderate Intensity Continuous Exercise Training Moderate Intensity Continuous Exercise Training Nordic Walking Nordic Walking Nordic Walking High Intensity Interval Training High Intensity Interval Training High Intensity Interval Training
- Primary Outcome Measures
Name Time Method Exercise Capacity Baseline to 12 weeks and Baseline to 26 weeks Changes in exercise capacity from baseline to 12 weeks and baseline to 26 weeks are measured by the six-minute walk test
- Secondary Outcome Measures
Name Time Method Functional Fitness Baseline to 12 weeks and Baseline to 26 weeks Changes in functional fitness from baseline to 12 weeks and baseline to 26 weeks are measured by the Senior Fitness Test
Aortic stiffness Baseline to 12 weeks and Baseline to 26 weeks Changes in aortic stiffness from baseline to 12 weeks and baseline to 26 weeks are measured by pulse wave velocity
Depression Baseline to 12 weeks and Baseline to 26 weeks Changes in depression from baseline to 12 weeks and baseline to 26 weeks are measured by the Beck Depression Inventory-II questionnaire
Quality of Life - HeartQoL Baseline to 12 weeks and Baseline to 26 weeks Changes in quality of life from baseline to 12 weeks and baseline to 26 weeks are measured by the HeartQoL questionnaire
Exercise Adherence Baseline to 12 weeks and Baseline to 26 weeks Changes in exercise adherence from baseline to 12 weeks and baseline to 26 weeks are measured by the Actigraph accelerometer
Body Composition Baseline to 12 weeks and Baseline to 26 weeks Changes in body composition from baseline to 12 weeks and baseline to 26 weeks are measured by body mass index.
Quality of Life - SF36 Baseline to 12 weeks and Baseline to 26 weeks Changes in quality of life from baseline to 12 weeks and baseline to 26 weeks are measured by the Short Form-36.
Depression mechanisms Baseline to 12 weeks and Baseline to 26 weeks Changes in depression mechanisms from baseline to 12 weeks and baseline to 26 weeks are measured by plasma kynurenine.
Lipid and glucose profile Baseline to 12 weeks and Baseline to 26 weeks Changes in lipid and glucose profile from baseline to 12 weeks and baseline to 26 weeks are measured by plasma Hemoglobin A1c
Trial Locations
- Locations (1)
University of Ottawa Heart Insititue
🇨🇦Ottawa, Ontario, Canada