ISRCTN34822127已完成未知
A prospective randomised controlled trial comparing the effects of fluid restriction with no active hyponatremia treatment on rate of change of plasma sodium, and markers of hyponatraemia related morbidity, in patients with chronic hyponatremia due to the syndrome of inappropriate antidiuresis.
Beaumont Hospital0 个研究点目标入组 46 人开始时间: 2018年4月27日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 46
研究概览
简要总结
2020 Results article in https://pubmed.ncbi.nlm.nih.gov/32879954/ results (added 05/08/2021)
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Age > 18 years
- •2. Chronic hyponatraemia with plasma sodium 120 - 130 mmol/L
- •3. Euvolemia and biochemical confirmation of SIAD.
排除标准
- •1. Symptomatic hyponatraemia
- •2. Plasma sodium < 120 mmol/L
- •3. An underlying cause for hyponatraemia is recognised which is temporary or rapidly reversible with treatment of the underlying condition or removal of the causative medication
- •4. Hypo- or hyper-volemia
- •5. Diuretic therapy
- •6. Uncontrolled hyperglycaemia (blood glucose > 16.6 mmol/L)
- •7. Pregnancy
研究者
相似试验
已完成
不适用
Comparing different types of jet ventilation during endobronchial ultrasound guided transbronchial needle aspiratioEBUS-TBNA +/- tumour biopsyCancerISRCTN58911367Medical University of Vienna90
已完成
不适用
sing dental ceramics in treating patients with worn teeth. A randomized clinical trial.Oral HealthTooth wearISRCTN16324420ational Dental Eastman Institute (Folktandvården Eastmaninstitutet)132
已完成
不适用
The Safety And efficacy of digital telereView for the follow-up of patients with abdominal pain: a randomised-controlled trial (RCT) Evaluating the Doctorbell platform (SAVED trial)ISRCTN28468556Singapore General Hospital70
已完成
不适用
The treatment of chronic anal fissures with fissure excision and Botulinum Toxin Type A injectioChronic anal fissureDigestive SystemISRCTN97413456State Scientific Centre of Coloproctology52
已完成
不适用
World hip trauma evaluation five: a randomised controlled trial comparing cemented and uncemented implants for the treatment of displaced intracapsular hip fracturesMusculoskeletal DiseasesFracture of neck of femurHip fractureISRCTN18393176niversity of Oxford1,125