A study to compare the clinical efficacy and quality of life in patients after treatment with cyclosporine eye drops versus chloroquine eye drops in dry eye disease.
Not Applicable
- Conditions
- Health Condition 1: H188- Other specified disorders of cornea
- Registration Number
- CTRI/2024/08/072597
- Lead Sponsor
- Dr Ekroop Kaur
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients with symptoms of moderate to severe dry eye.
Patients with findings of dry eye on slit lamp examination.
Exclusion Criteria
Patients with history of ocular surgery or ocular trauma in last 2 months.
Patients with history of contact lens use in last 2 months.
Patients with active ocular disease other than dry eye like uveitis, keratitis, conjunctivitis etc.
Patients allergic to fluorescein stain.
Patients with history of allergy to either of the test drugs.
Patients unable to undergo Schirmer’s test or slit lamp examination and hence TBUT.
Patients unable to understand regional language or English and hence understand OSDI questionnaire.
Pregnant females.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Assessment and comparison of clinical efficacy of topical chloroquine 0.03% versus topical cyclosporine 0.05% in patients with moderate to severe dry eye disease by means of testing for Schirmer test, Tear film breakup time and OSDI score.Timepoint: 1 month
- Secondary Outcome Measures
Name Time Method ILTimepoint: NI